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Particularly in groups receiving 600 and 900 mg/kg, erythrocyte immunoadhesive function was notably compromised, as demonstrated by a significant decrease in erythrocyte C3b receptor rosette rate (E-C3bRR) and an increase in erythrocyte immune complex rosette rate (E-ICRR) ( 5 Erythrocytes in pathogen recognition and responses Erythrocytes play a crucial role in pathogen recognition and immune responses

In terms of lipid metabolism, HFD upregulated hepatic expression of genes involved in lipid uptake ( Cd36 ) and decreased expression of genes for de novo lipogenesis ( Fasn ) and lipid binding ( Fabp1 )

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