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10.1016/j.mce.2011.06.015 57 InoueT.MikiY.AbeK.HatoriM.HosakaM.KariyaY.et al (2012)
Mutallip, M
FDA Approval Whether the patent was filed before or after a drug was approved by the U.S.FDA and available on the U.S market
"This is something that Indian generic players have been preparing for a very long time," Salil Kallianpur, an independent pharma consultant based in India, told CNBC
Its therapeutic value lies in its ability to selectively induce apoptosis in senescent cells by disrupting the FOXO4-p53 interactome, a mechanism that evades the collateral cytotoxicity often seen with broader senolytics like Navitoclax (Huang et al., 2021)
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