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Combining these agents without strict medical oversight can amplify cardiovascular strain, elevate blood pressure, and increase the risk of arrhythmias, which is why most physicians advise against simultaneous use

For example, people with type 2 diabetes may be more likely to experience low blood sugar on semaglutide, especially if they are also taking insulin, which also helps to lower blood sugar levels

Cancer Res (2011) 71(7):245565

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That said , the study provides useful reassurance about the safety of this class of drugs

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