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Psoriasis pathogenesis involves ROS derived from upregulated NOX2/p67phox in keratinocytes, driving metabolic reprogramming via AMPK inactivation and HIF-1 stabilization

ECs are arranged side-by-side, creating a semi-permeable monolayer, the endothelium [3]

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doi: 10.1016/j.tox.2013.02.014 59 ChiHHuangJYanYJiangCZhangSChenHet al

25,26 Cardiovascular diseases like cardiomyopathy, and neurodegenerative diseases such as Alzheimers disease, can be attributed to abnormal energy supply