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220 One of the most critical effectors of AKT is mTOR, a kinase that exists in two complexes: mTORC1 and mTORC2

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Although mechanisms describing the interaction between the key pathway constituents Nrf2, Keap1 and p62 are widely reviewed and discussed in literature, quantitative dynamic models bringing together these mechanisms with time-resolved data are limited

doi: 10.1038/s41580-020-00324-8 31 ThompsonJMAlvarezASinghaMKPavesicMWNguyenQHNelsonLJet al