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Nausea, vomiting, diarrhoea, and constipation are reported frequently, especially during dose escalation

Although breast cancer cell lines exhibit increased resilience to physiologically relevant shear stress compared to normal epithelial cells [223], lamin A/C knockdown exacerbates shear stress-mediated tumor cell death [223], suggesting that elevated lamin A/C levels could aid breast CTCs in withstanding shear forces in the circulation

Diabetes Care, 39 , 20652079

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J Dermatol Sci 2010;58:85-90

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