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3.2.2 Thrombosis Research indicates that adverse cardiovascular outcomes, including arterial thrombosis and mortality (Tang et al., 2013

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Diagnostic applications The unique features of MSNs, such as their adjustable size and surface properties, make them highly promising for use in imaging applications

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Standard titration (what guidelines say) Regulators and NHS guidance recommend: * 2.5 mg once weekly for 4 weeks (initiation) * Then 5 mg once weekly for at least 4 weeks * Then optional increases in 2.5 mg steps at intervals of at least 4 weeks if further weight or glucose control is needed and the patient tolerates the current dose * Maintenance doses: 5, 10 or 15 mg once weekly * Intermediate strengths (7.5 and 12.5 mg) exist specifically to allow slower titration they are not intended as long-term maintenance doses