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Clinically, this often surfaces as cognitive fatigue, difficulty with memory retrieval, and the phenomenon that many women describe as "menofog," a pervasive sense of mental cloudiness that is not simply tiredness but reflects a genuine disruption in how brain cells are producing and managing energy [2]

Patient selection criteria are not well-established, and determining which patients are most likely to benefit from these therapies requires clinical judgment based on limited evidence

2003 Oct;56(5):270-4

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With fewer red blood cells to carry oxygen, your heart and lungs may work harder, which can lead to breathlessness or a faster heartbeat