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The Journal of clinical endocrinology and metabolism

Hyperphagia and Increased Fat Accumulation in Two Models of Chronic CNS Glucagon-Like Peptide-1 Loss of Function

Its ability to reduce inflammation and oxidative stress positions it as a promising adjunct therapy for conditions such as diabetes mellitus, pancreatitis, and pancreatic cancer

Nutritional strategies should emphasize whole foods, adequate protein intake (0.81.0 g/kg body weight, adjusted for kidney function if needed), and mindful portion control rather than severe caloric restriction, which can further suppress metabolic rate

The study included 3,746,672 people with type 2 diabetes, of whom 4,466 developed thyroid cancer

GLP-1 therapies remain expensive, and insurance coverage varies