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NAD+ precursors like NR are classified as dietary supplements in the United States and are not subject to the same rigorous interaction studies required for prescription medications
The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants
These three supplements taken together have a synergistic effect
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10.1016/j.jpba.2023.115914 J Pharm Biomed Anal
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