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Pinocytosis appears to be important for the transport of some big molecules (e.g., insulin across the blood brain barrier), but not for small molecules like most drugs

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VLDLR is significantly higher expressed in thermogenic (brown and beige) adipocytes than in white adipocytes 54 , and vLDLR-mediated vLDL uptake is a crucial pathway fueling thermogenesis in BAT 55

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