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An imbalance of certain chemical messengers in the brain, notably serotonin , also plays an important role in the onset and intensity of attacks

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It works by modulating the GABAergic system in the brain, which can promote relaxation, reduce symptoms of anxiety, and improve sleep quality

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The meta-analysis used both random-effects and fixed-effects models to evaluate pooled risk ratios (RRs) and 95% confidence intervals (CIs)

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