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Nature 580 , 530535 (2020)

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The brain junctional molecules include tight junctions (TJs), adherens junctions (AJs), and gap junctions, which collectively impede the paracellular movement of solutes [13,14,15,16]

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In the case of acute gout, which is characterized by simultaneous hypoxia and inflammation, the modulation of HIF-1 expression becomes crucial for therapeutic intervention [51, 52]

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