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The masses that develop in women with lipedema and metabolic syndrome are similar to those that develop on the abdomens of people who have obesity and do not have lipedema

doi: 10.1007/BF02182342

A 2018 paper Targeting Mitochondrial Dysfunction and Oxidative Stress in Activated Microglia using Dendrimer-Based Therapeutics out of Johns Hopkins University Center for Nanomedicine described an improved dendrimer-NAC conjugate called TPP-D-NAC which was able to target the dysfunctional mitochondria found in activated microglial cells and reduce oxidative stress levels substantially as well

Vit D Blood Level Optimization (at least 75 nmol/L) should not get overlooked in this scenario either

Reduces muscle fatigue and improves energy levels