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In: Reference Module in Biomedical Sciences

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Heritage and perspectives POMC and its derivatives have been discovered over nearly a century: alpha-MSH identification by Harris in the 1950s, POMC characterization by Nakanishi and Numa (Nature, 1979), cloning of the five MC1R-MC5R receptors between 1992 and 1994 (Cone, Mountjoy, Gantz teams)

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Conclusion CJC-1295 remains an unapproved, investigational peptide with early-phase studies showing potential for GH/IGF-1 stimulation [pubmed.ncbi.nlm.nih.gov]