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Moreover, H 2 S exerts a protective effect against various apoptotic stimuli through the activation of NF-B and Nrf2 mediated by H 2 S-linked persulfidation (32, 33)

The resulting elevated concentrations of homocysteine and MMA are often found in patients with low serum vitamin B 12 and can usually be lowered with successful vitamin B 12 replacement therapy

With respect to fatty acid metabolism, CYP2E1 catalyzes the microsomal (-1)- and (-2)-hydroxylation of saturated fatty acids and the epoxidation of unsaturated fatty acids

Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD(+) redox