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The most common side effects of GLP-1 receptor agonists are gastrointestinal symptoms including nausea, vomiting, diarrhoea, and abdominal discomfort, particularly during treatment initiation

Despite clear guidance, adherence challenges remain common

Across both drugs, persistence rates among patients on GLP-1 therapy for obesity is meaningfully lower relative to the type II diabetes cohort

The ramifications of this trend are profound, with health care professionals noting a surge in the early onset of type 2 diabetes, cardiovascular diseases, and mental health issues such as depression and social isolation among the younger population

This upgrade allows you to benefit from the additional GIP receptor activation found in Tirzepatide

Acknowledgments We would like to thank the laboratory staff who are actively involved in the preparation of this work