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However, the larger ACT trial (n=2,308) did not confirm this benefit (ACT Investigators, Circulation, 2011) [68]

M.Alcocer-GmezE.Castejn-VegaB.Navarro-VillarnE.Conds-HervsM.Mundi-RoldanM.et al (2021)

Recently, we reported that not only the acute infectious phase [25] but also Long COVID [26] is characterized by concurrent elevations in depression (depressed mood, feelings of guilt, suicidal ideation, loss of interest), anxiety (anxious mood, tension, fears, anxiety behavior at interview), chronic fatigue and somatic symptoms including autonomic and gastrointestinal (GIS) symptoms, malaise and muscle pain

Animal studies have offer mechanistic insights into this subject

Whats worse, patients with T2D were observed a decreased expression of GLUT1/2, which reduce intracellular transportation of glucose, thus producing less ATP and impaired insulin releasing

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