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Notably, usage of these drugs has escalated dramatically, with prescriptions increasing fortyfold since 2018, culminating in over 15 million Americans using these drugs as of the last month
However, GLP-1 receptor agonists are large, complex molecules
The move could significantly expand access to these treatments for people with diabetes and obesity
For example, back pain and musculoskeletal discomfort appear in certain GLP-1 agonist SmPCs as uncommon or common adverse reactions
Both the STEP-1 and SURMOUNT-4 trials included the availability of RDN dietary counseling and recommendations to exercise 150 min/week during the treatment period, but with notable weight regain for most participants upon GLP-1 discontinuation without continued nutrition support [18,273]
Most adults (70%) who have taken GLP-1 drugs say their insurance covered at least a part of the cost of these drugs, including about half (48%) who say their insurance covered part of the cost of these drugs and about one in five (22%) who say their insurance covered all of the cost
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