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Since TGR5 is expressed in intestinal neurons, a reduction or deficiency of TGR5 receptors can disrupt intestinal epithelial tight junctions, thereby affecting intestinal motility ( The metabolic pathway of bile acids, encompassing bile production, conversion, excretion, and reabsorption, constitutes the enterohepatic cycle of bile acids

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Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential