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This review systematically examines metformins therapeutic mechanisms in PCOS management, while assessing its clinical impacts across critical developmental phasesfrom pubertal maturation through gestation to long-term health maintenance

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Using DNA microarray solutions such as the EUROArray system (EUROIMMUN, Germany), the identification of the disease-associated alleles HLA-DQA1- and HLA-DQB1, which code for the subunits HLA-DQ2.2, -DQ2.5 and -DQ8, can be done