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The concentration of this receptor was also reduced in the hippocampus of prenatally stressed rats subsequent to a 12-week high-fat diet [84]

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Similarly, hepatic steatosis is closely linked with HFpEF, often co-existing and contributing to systemic inflammation and metabolic dysregulation 79

It is contraindicated in patients with a personal or family history of Medullary Thyroid Carcinoma (MTC) or MEN 2, or a history of pancreatitis

Equol, a dietary daidzein gut metabolite attenuates microglial activation and potentiates neuroprotection in vitro