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Strengths and Limitations This systematic review and meta-analysis was strengthened by the incorporation of recently published studies, by addressing the increased risks of biliary diseases with GLP-1 RA use separately from gallbladder disorders, and by highlighting the increased risk associated with other GLP-1 RA medications, in addition to liraglutide
Importantly, probiotics should never be used as a substitute for prescribed GLP-1 receptor agonists or other diabetes/weight management therapies
Activating two important hormone pathwaysGLP-1 and GIP receptorscan also reduce appetite and support weight loss in some individuals
If some identified proteins were not annotated by the UniProt-GOA database, InterProScan software (a sequence analysis application) was used to annotate the proteins GO function based on the protein sequence alignment method
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