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Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum

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published in Molecular Brain confirmed endogenous MGF expression in neurogenic brain areas with age-dependent decline, and that transgenic MGF overexpression significantly increased BrdU+ proliferative cell counts in the dentate gyrus and subventricular zone of the hippocampus establishing MGF as a neurogenesis-promoting factor in ageing brain biology and directly relevant to PEG-MGF neurogenesis and neuroprotection research applications

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doi: 10.1155/2021/3361309 71 DaniilopoulouIVlachouELambrouGINtikoudiADokoutsidouEFasoiGet al

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Bull Exp Biol Med 2003;135:5902

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