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doi: 10.3892/mmr.2014.2734 81 ChenZHuangCMaTJiangLTangLShiTet al

Beyond directly influencing pathological changes in the AD brain, BAs may provide neuroprotective benefits by modulating the microbiotagutbrain (MGB) axis, which supports memory function

Functional interactions often involve specific hydrogen bonds and, in some cases, salt bridges, whereas nonfunctional interactionslacking evolutionary selectionare primarily driven by hydrophobic effects 63

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