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Consulting a doctor before starting supplementation is advisable, particularly for individuals with medical conditions or those taking prescription medications
The cooperation between Asc and phenols has been shown within the hydrogen-peroxide-peroxidase system which takes place in vacuole where H 2 O 2 diffuses and may be reduced by peroxidases, and phenols are used because of the primary electron donors
In this review we will focus on (a) GSH depletion as a fundamental risk factor for diseases like chronic obstructive pulmonary disease and atherosclerosis (ischemic heart disease and stroke), (b) importance of oxidative stress and antioxidants in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19 disease, (c) significance of GSH to counteract persistent damaging inflammation, inflammaging and early (premature) inflammaging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses in younger individuals, and (d) new therapies that include antioxidant defenses restoration
PMID 18154548
PMID: 39747971 Brain Res Bull Nerol ameliorates cognitive dysfunction in vascular dementia rats by inhibiting mitochondrial oxidative stress and reducing hippocampal senescence