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Compared with other GLP-1 RAs, tirzepatide is associated with a similar rate of gastrointestinal adverse events but a higher risk of drug discontinuation due to adverse drug events when used at higher doses (10 or 15 mg subcutaneous once weekly)

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Purity assessment

The evidence base for use of these drugs, either for off-label indications or as non-approved drugs, is wanting

Potential role of indolelactate and butyrate in multiple sclerosis revealed by integrated microbiome-metabolome analysis

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