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Importantly, FOXO4-DRI showed no significant toxicity towards normal TM3 Leydig cells, demonstrating its selective action against senescent cells

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Stewart LJ, Ong CLY, Zhang MM, Brouwer S, McIntyre L, Davies MR, Walker MJ, McEwan AG, Waldron KJ, Djoko KY (2020) Role of glutathione in buffering excess intracellular copper in Streptococcus pyogenes