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Dose Is the Lever That Controls Most Side Effects DAC dosing and side-effect incidence: 0.5 mg per injection: very few reports of anything 1 mg per injection (1 to 2 mg weekly): the standard range, mild side effects in some users 2 mg+ per injection: water retention and tingling reports climb noticeably No-DAC dosing and side-effect incidence: 100 mcg per injection: essentially side-effect-free for most users 200 to 300 mcg per injection: occasional mild headache 500 mcg+ per injection: more headache and flushing reports My honest take: most side-effect complaints I see come from people who jumped to the top of the dose range in week one

Another reason B12 supplements may trigger acne is because many versions found on store shelves are synthetic

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