Some patients notice reduced stiffness and better energy within a few months, alongside gradual improvements in inflammation markers
One expert suggested a good enough drug with sufficient drug supply may be able to penetrate the market that the demand seems greatly outweigh the supply
The FDA emphasized that compounded drugs are not FDA approved and therefore are not reviewed by the agency for safety, effectiveness, or quality before marketing
57 Budak et al 58 found that exenatide increased the antioxidant capacity of human monocytes/macrophages in vitro, reducing oxidative stress by decreasing the expression of ROS-producing NADPH oxidase, increasing the expression and activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and decreasing ROS and malondialdehyde (MDA) levels
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There are also the side effects like nausea, vomiting and constipation associated with the buildup of food and waste in the digestive tract