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As the body adjusts to the medication and losing weight, menstrual cycles often return to normal

In this answer 3 sections The reason you started with intense every other day B12 shots and transitioned to a monthly schedule is a medical strategy called loading and maintenance. When you were first diagnosed, your bodys B12 stores were dangerously low

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doi:10.1038/nature03000 Sosne G, Kleinman HK, Springs C, Gross RH, Sung J, Kang S