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Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis

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Transition metalbased carriers (e.g., MnO, Cu 2 , Fe 3 ) provide an additional layer of functionality, as they can both deplete intracellular GSH and generate reactive oxygen species, thereby amplifying oxidative stress within tumors

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This article provides a consolidated research overview of all three products and how they relate to each other