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Unfortunately, NAD+ levels decline with age, stress, poor diet, and metabolic dysfunction

Insider's takeaway Vitamin B12 injections are for those with a severe B12 deficiency or conditions that prevent their body from effectively absorbing the vitamin, Moreno says

A decrease in NAD+ adversely impacts cellular energy metabolism, while a reduction in SAM hinders the activation of genes that are vital for boosting metabolism

See the visual reconstitution guide for handling steps and the FAQ for alternate dilutions and injection details

Protocols, doses, and reactions reported below come from preclinical animal research and self-reported community sources

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