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doi:10.31080/ASNE.2024.07.0731 9

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At the same time, if a particular formula is potentially stronger but not as well studied, research becomes less predictive, and the side effects could outweigh health benefits

Severe or persistent diarrhea warrants dose reduction, temporary discontinuation, or trial of a different GLP-1 formulation

Since then, Novo Nordisk (Wegovy and Ozempic) and Eli Lilly (Mounjaro and Zepbound) have struggled to manufacture enough product and both of Novo Nordisk's semaglutide medications have been on the FDA's shortage list since early 2022