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Obesity makes bile more saturated with cholesterol, and diabetes can delay gallbladder emptying, both of which increase the risk

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Eating smaller meals, avoiding high-fat or spicy foods, and staying well hydrated may help

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Since taking lipoic acid with a meal decreases its bioavailability, it is generally recommended that lipoic acid be taken 30 min prior to a meal (see also Metabolism and Bioavailability) (8)