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Maximum benefits typically develop over 2-4 weeks as B12 levels normalize throughout your body

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Patients with this type of bile acid diarrhea have significantly lower FGF19 and higher 7a-hydroxy-4-cholesten-3-one (C4) levels than healthy controls (169), which supports the hypothesis that excess synthesis of bile acids may overflow the reabsorption capacity in the ileum and hence allow bile acids to enter the colon in larger quantities

At the first measurement, average milk levels were approximately 1,200 pmol/L (1,650 ng/L) in the supplemented group and 900 pmol/L (1,220 ng/L) in the nonsupplemented group