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Although direct evidence for GLP-1RA use in PsA remains limited, the inclusion of PsA populations in these tirzepatide trials represents a conceptual shift toward testing immunometabolic interventions in inflammatory arthritis rather than restricting their evaluation to skin disease alone

Acute cholecystitis: Persistent RUQ pain beyond 4-6 hours, fever above 38.5C, positive Murphy's sign on exam, elevated white cell count

However, HE staining showed that the vacuoles of hepatocytes in the L-carnitine + perhexiline maleate (before operation) group were significantly higher in number than those in the L-carnitine (before operation) group and the control group at 3 time points

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