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A 2024 meta-analysis of 35 RCTs found selenium supplementation significantly reduced TPO antibodies, TSH, and oxidative stress markers in Hashimoto's patients - effects mediated through the GPx-glutathione system

Paired t-tests were performed for datasets that exhibited a normal distribution

[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Lettieri G., Mollo V., Ambrosino A., Caccavale F., Troisi J., Febbraio F., Piscopo M

Studies have revealed that IF increases microbial diversity, particularly enriching beneficial taxa such as Bifidobacteria and Akkermansia muciniphila , which are crucial for maintaining gut barrier integrity, reducing intestinal permeability, and supporting systemic metabolic health [80]

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