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These results further elucidate the acute response of monocytes to BDG and establish a novel role for glutathione metabolism in monocyte biology

Current therapeutic approaches, such as disease-modifying anti-rheumatic drugs (DMARDs) and biologics, are limited by infection risks, poor tissue specificity, and suboptimal long-term efficacy, underscoring the need for novel therapies

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Chest 130 , 15111519 (2006)

Secondly, it could dampen the immune response