- Interactions: High-dose vitamin B12 supplements can, in isolated cases, affect the efficacy of certain medications
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This transition involves upregulation of markers such as CD206, Arg1, and IL-10, enhanced efferocytosis of apoptotic cells, and secretion of growth factors like VEGF, TGF-, and FGF2, which promote angiogenesis, fibroblast activation, and ECM remodeling [41]
Hepatocellular Carcinoma (HCC) and Liver Metastases ( HCC HCC Hepatocellular carcinoma (HCC) typically arises in a chronically diseased or cirrhotic liver and is the most common primary liver cancer
These insights provide a metabolic rationale for ketogenic-based therapies in AGC1 deficiency and related neurological syndromes with overlapping metabolic and neurodevelopmental abnormalities