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Hypoxia-driven autophagy is another protective mechanism activated in cancer cells that can lead to chemoresistance under hypoxic conditions (185187)

Under high glucose conditions, in 661W cells and photoreceptor cells of diabetic mice, the expression of GPX4 and SLC7A11 is downregulated, while the expression of ACSL4, FTH1, and NCOA4 is upregulated

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Interestingly, antioxidant genes of plants and fungal pathogens including GSTs were distinctly regulated during disease development in different R

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and when two cysteines are involved, disulfide formation