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methylmalonic acid, MM-CoA

TSH testing serves as the initial screening tool, with elevated levels indicating hypothyroidism present in approximately 15% of hair loss patients [1]

For patients with type 2 diabetes and biopsy-proven NASH with fibrosis, pioglitazone may be considered under specialist supervision, as its use for liver disease is outside its licensed indication (type 2 diabetes) and requires careful assessment of potential risks and contraindications

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During B 12 deficiency, this reaction cannot proceed, which leads to the accumulation of levomefolic acid