This increased comfort may translate into higher engagement, improved adherence, and a broader patient population seeking medical weight loss support
For brand-name Mounjaro and Zepbound, the manufacturer recommends against returning the medication to the refrigerator once it has been stored at room temperature
In animal studies, mice fed thermo-induced oxidized oil (TIOO) diets displayed disrupted ceramide and sphingomyelin levels (86)
Immediate Management If hypoglycaemia occurs: Break the fast immediately this is medically necessary Have 15-20g fast-acting carbohydrates: 3-5 dates 120ml fruit juice 3-4 glucose tablets Wait 15 minutes and reassess symptoms If symptoms persist: Have another 15-20g carbs and seek medical attention Prevention Strategies Ensure adequate complex carbohydrate intake at Suhoor (covered in Part 2) Never skip Suhoor this is critical when on GLP-1s Monitor symptoms closely, especially in Week 1 of Ramadan Consider dose reduction if on higher doses (Mounjaro 10mg+, Wegovy 1.7mg+) Keep glucose tablets handy if on higher doses Important: The risk is LOW in non-diabetic patients, but being prepared is essential
2025;DOI:10.1016/j.jaci.2025.09.027
Astra and Zeneca merge around this time
