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In this trial, 203 obese individuals were divided into four groups: placebo, 0.25 mg, 0.5 mg, and 1 mg Tesofensine daily

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However, SOD and CAT in plasma, erythrocytes and gingival tissues were elevated, whereas activities of non-enzymatic antioxidants (vitamins E, vitamin C, and reduced glutathione) decreased in periodontitis [26]

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