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Best practice: inject on an empty stomach, ideally before bed or first thing in the morning after an overnight fast

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50 LiuZ.Cordoba-ChaconJ.KinemanR.CronsteinB.MuzumdarR.GongZ.et al (2016)

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Its not a magic bullet that makes you skinny overnight, but its a consistent, measurable change

It is prolonged, cumulative exposure that causes measurable degradation