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Real World Data Beyond Clinical Trials Clinical trials provide controlled environments with strict monitoring, but real world data captures how GLP-1 medications perform in everyday use

Sumithran P, Prendergast LA, Delbridge E, Purcell K, Shulkes A, Kriketos A et al

FDA.gov (accessed 2 September 2025)

Moon S, Lee J, Chung HS, Kim YJ, Yu JM, Yu SH, et al

27 Importantly, meta-analyses suggest that patients with lean MASLD may have a higher all-cause mortality rate than those with nonlean MASLD (hazard ratio 1.61, 95% confidence interval 1.371.89), independent of traditional risk factors