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Lf can mediate receptor-mediated transcytosis, increase BBB permeation, and bind to the DA cells that are rich in Lf receptors, thus increasing the specificity and ensuring the safety of the therapeutic agent's route

Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate-to-severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2)

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Yes, research demonstrates that long-term creatine supplementation can improve bone health by increasing osteoblast activity and reducing bone resorption

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185 In addition, aptamers are widely used in drug delivery, clinical diagnostics, and biosensing