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[1] Symptoms usually begin between the ages of 5 and 35 years

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Although rare, serious side effects have been noted, with gallbladder disease and pancreatitis among the most concerning

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Future research should prioritize long-term safety assessments, efficacy evaluations in specific populations, exploration of novel indications (eg, metabolic-associated fatty liver disease and obstructive sleep apnea), and mechanistic studies to enhance the therapeutic utility of these agents in metabolic and related diseases (See Figure 7)

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