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Clean Food, No Refined Ingredient Skip the heavily processed foods with questionable ingredients and refined sugars

Pigmentation is most pronounced at the tips of often elongated, club-shaped rete ridges ( Fig

Relevant markers include malondialdehyde (MDA), 8-isoprostane, reduced glutathione (GSH), and high-sensitivity CRP

Yang CT, Yao WY, Yang CY, Peng ZY, Ou HT, Kuo S

Amino acid metabolism in DKD exhibits paradoxical effects: while BCAAs activate mTORC1 signaling leading to insulin resistance and podocyte injury, sulfur amino acid-derived H 2 S confers renoprotection through Nrf2 activation, whereas homocysteine accumulation promotes vascular damage (Figure 3)