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Kynurenine was the top predictor of NAC effect in SLE (AUC = 0.851)

Chinnery, PF, Turnbull, DM 2001, Epidemiology and treatment of mitochondrial disorders, American Journal of Medical Genetics , vol

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This suggests a crucial role for Ru II -01 in modulating NRF2, depending on p53 status, for successful cancer cell responses to therapy ( Ru II -01 is hydrophobic in the cellular environment, which makes its efficient delivery to target sites difficultAccordingly, Ru II -01 was incorporated into hydrophobic compartments of various nanoassemblies, such as liposomes, micelles, and coacervate nanodroplets

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